SLC2A5 and cholangiocarcinoma: GLUT5 silencing has also led to upregulation of the epithelial-like cell marker, E-cadherin, and downregulation of the mesenchymal-like cell marker, N-cadherin, implying that GLUT5 may influence the metastatic potential of CCA cells by regulating epithelial-to-mesenchymal transition (EMT) processes (Suwannakul et al. 2022).