SLC2A5 and breast cancer: Notably, [18F]-labeled 6-deoxy-6-fluoro-D-fructose (6-[18F]FDF) has been employed in PET imaging to visualize BC, leveraging GLUT5’s role in mediating the transport of 6-[18F]FDF and its consequent accumulation in BC cell lines (Wuest et al. 2011, 2018; Trayner et al. 2009) (Fig. 2).