Meanwhile, the H3K27ac of four common cancers, K562 (bone cancer), HCC827 (lung cancer), T24 (bladder cancer), and CAL51 (breast cancer), were visualized, had low H3K27ac levels at the DKK1-SE regions, demonstrating that histone modification information in this region is not widespread (Fig. 1A). The gene discussed is DKK1; the disease is cancer.