Association between CYP4F3 expression and TP53 mutation status in CRC; C. Analysis using GEPIA2 reveals a positive correlation between CYP4F3 expression and NRF2 levels in CRC tumor tissues from TCGA dataset; D. Analysis using GEPIA2 demonstrates a significant negative correlation between CYP4F3 expression in normal intestinal tissues from TCGA and GTEx datasets and NRF2 expression. The gene discussed is CYP4F3; the disease is neoplasm.