However, recent reports on the mechanismof tumor-targeted antibody-mediated depletion in preclinical modelshave shown that activating FcγR-expressing monocytes and macrophagesare the key cell types responsible for cytotoxicity against tumorcells in vivo.(48,49) Using our preparedhomogeneous glycan IgG library, interaction with other FcγRscould be measured. The gene discussed is FCGR2A; the disease is neoplasm.