KLK3 and posterior cortical atrophy: The Barcelona-MRI predictive model (BCN-MRI PM) for individualizing the risk of csPCa detection in prostate biopsies was developed due to the absence of csPCa risk calculators using the Prostate Imaging Reporting and Data System (PI-RADS) v2.0, and six other independent clinical predictive variables without range limitations, namely: age (years), PCa family history (no vs. yes), type of prostate biopsy (initial vs. repeated), serum PSA (ng/mL), digital rectal examination (DRE: normal vs. suspicious), MRI-derived prostate volume (mL), and PI-RADS score from 1 to 5 (7).