Conversely, women with T2D who were not receiving medical treatment or had a shorter treatment duration showed no elevated risk for fractures, a finding supported by recent large cohort studies from Sweden.5,6 Results from this study agree with findings from a comprehensive analysis6 of 580 127 Swedish patients with T2D, reporting that insulin treatment and a long duration of T2D were associated with increased fracture risk. The gene discussed is INS; the disease is type 2 diabetes mellitus.