Then, the nanoparticles who reachthe heart are ejected into the circulation albeit a major blood flowis directed into the lungs, which contain a fine network of microvessels.33 Augmented numbers of FRβ+ myeloidcells were detected in the lungs of tumor-bearing animals; accordingly,this organ specifically became a target for the cyclodextrin nanoparticlesconjugated with folate. This evidence concerns the gene FOLR2 and neoplasm.