MRC1 and cancer: Cancer affects immunefunctions and hematopoiesis; the cells of myeloid origin increasein number, show immature characteristics, and acquire pro-tumor functions.29 In this study, mice bearing 4T1 mammary tumorswere used as a typical cancer model wherein myeloid subset of theimmune cells is considerably altered.39,40 We first determinedthe time-dependent increase in classical macrophages, CD206+ macrophages, granulocytes, and monocytes as cancer progressed.