Analysis of human ccRCC cell lines and an immortalized human proximal tubule cell line, HK-2, found varying relative expression of ANGPTL4, with similar expression in 786O and HK-2 cells, with 786O expression being slightly lower, and the highest expression in CAKi-1 cells (Fig. 1C). This evidence concerns the gene ANGPTL4 and nonpapillary renal cell carcinoma.