TYR and melanoma: In another study, monophenolic derivatives 4‐hydroxyphenol and raspberry ketone showed TYR‐induced cytotoxicity in B16 melanogenic melanoma cells, leading to vacuolization, while 1 did not exert any significant impact on cell viability.[23] This suggests that while leukoderma induced by monophenols may stem from toxic ortho‐quinone production due to TYR catalytic activity, the lack of effect observed with 1 implies that this compound, along with potentially other resorcinol derivatives, acts as a genuine inhibitor in cellular assays.