Some PBC-FMT–related hepatic signaling pathways in mice, such as the hematopoietic cell lineage pathway, Toll-like receptor signaling pathway, graft-versus–host disease pathway, and PPAR signaling pathway, are the same as those altered in PBC patients but were not altered patients with ALD, HBV, HCV, HCV cirrhosis, or NASH for whom the transcriptome is available. Here, PPARA is linked to Cirrhosis.