UCHL1 and Alzheimer disease: In AD, abnormalities in Parkin (an E3 ligase), ubiquitin C‐terminal hydrolase L1 (UCH‐L1) (a DUB), HRD1 (an E3 ligase), and the C‐terminus of Hsc70‐interacting protein (CHIP) (an E3 ligase) have been reported.