The phosphorylation of Rab10 at the Thr‐73 residue (pThr73–Rab10) can hinder ciliogenesis in holinergic interneurons. pRab10 is primarily found in abundance at the presynaptic terminal. In addition, higher levels of pT73–Rab10 are probably linked to more severe PD progression. The gene discussed is RAB10; the disease is Parkinson disease.