NEUROD1 plays a critical role in the functional development of the endocrine pancreas, as Neurod1 gene deletions are postnatally lethal within a few days after birth due to severe diabetes (Bohuslavova et al., 2021; Naya et al., 1997; Romer et al., 2019; Bohuslavova et al., 2023). Here, NEUROD1 is linked to diabetes mellitus.