Recent studies employing systematic or tissue-specific deletions of the Neurod1 gene have revealed a consistent pattern of neurological abnormalities alongside a severe neonatal diabetes phenotype (Bohuslavova et al., 2021; Naya et al., 1997; Romer et al., 2019; Bohuslavova et al., 2023). The gene discussed is NEUROD1; the disease is diabetes mellitus.