Therefore, it is necessary to inhibit ACE to regulate blood pressure and treat hypertension; synthetic inhibitors, including lisinopril, captopril, losartan, atenolol, and hydralazine, are used for medical treatments; however, they may have adverse effects, including inflammatory response, dry cough, taste disturbance, skin eruptions, or angioneurotic edema [85]. Here, ACE is linked to hypertensive disorder.