APOH and autoimmune polyendocrinopathy: Treatment with oral vancomycin of APS (NZW x BXSB)F1 mice reduces anti-β2GP1 immunoglobulin G (IgG) titers, decreased cerebral, cardiac and pulmonary thrombi, and improves survival.7In systemic lupus erythematosus, a disease that strongly overlaps with APS, transfer of healthy microbiome to patients with therapy-unresponsive disease flares appears to diminish disease activity.8