The peripheral lymphocyte, T lymphocyte, CD4+ T cell, CD4+CD28+ T cell, and CD8+CD28+ T cell counts were also lower among the non-survivors with sepsis than among the survivors (425 versus 797, P=0.015; 315 versus 597, P=0.028; 180 versus 401, P=0.031; 167 versus 357, P=0.015; and 36 versus 94, P=0.003, respectively) (Table 4; Additional File S6). This evidence concerns the gene CD28 and Sepsis.