TLR2 and neoplasm: By focusing on toll-like receptor 2 (TLR2) on macrophages, 1-steaoryl-2-15-HpETE-sn-glycero-3-phosphatidylethanolamine (SAPE-OOH) on the surface of ferroptotic cells works to transmit an eat-me signal, which directs phagocytosis and restricts the tumor growth (61).