Resident LAM-APOC1 was expressed both in the tumor and juxta-tumor area, strongly associated with CD8+ T cells and T-regs, while LAM-STAB1 was mostly expressed in the tumor and had a high level of TREM2 and IL-1B, suggesting their monocytic origin associated with poor prognosis (79). The gene discussed is IL1B; the disease is neoplasm.