ERBB2 and breast cancer: A comprehensive table (Supplementary Table 1) has been compiled to summarize the recent clinical trials incorporating Pertuzumab, Trastuzumab, and Pyrotinib in BC, which can be found on the website https://classic.clinicaltrials.gov/ct2/home.To our knowledge, this is the first case report on using three HER2-targeted drugs combined with docetaxel for the treatment of a locally advanced HER2-positive BC patient, resulting in the attainment of pCR.