Slc17a6, Slc1a2, Slc1a3, and Slc6a11 can potentially influence synaptic transmission in the cochlear nucleus (CN) region of auditory system because Slc17a6 and Slc1a3 are upregulated in noise-induced and age-related hearing loss (Tadros et al., 2007; Manohar et al., 2016) and Slc1a2 has been reported to play a crucial role in noise-induced cochlear synaptopathy by regulating glutamate clearance (Lavinsky et al., 2018). The gene discussed is SLC1A2; the disease is presbycusis.