Upregulated cyclin-dependent kinase inhibitor 1 A (p21), cleaved cysteinyl aspartate specific proteinase (caspase-3/caspases-9), and PARP but downregulated cyclin-dependent kinase 4 (CDK4) and X-linked inhibitor of apoptosis protein expression concomitant with the suppression of growth in breast carcinoma cells, also induced excessive ROS levels in BC cells. The gene discussed is CASP3; the disease is breast carcinoma.