As shown in Figure 4G, the KEGG signaling pathways of BA mainly involved the pathways of Lipid and atherosclerosis, Proteoglycans in cancer, Hepatitis B, Yersinia infection, Human cytomegalovirus infection, Fluid shear stress and atherosclerosis, Chagas disease, Toxoplasmosis, Th17 cell differentiation, and PI3K-AKT signaling pathway. This evidence concerns the gene PIK3CA and Chagas disease.