As shown in Figure 4G, the KEGG signaling pathways of BA mainly involved the pathways of Lipid and atherosclerosis, Proteoglycans in cancer, Hepatitis B, Yersinia infection, Human cytomegalovirus infection, Fluid shear stress and atherosclerosis, Chagas disease, Toxoplasmosis, Th17 cell differentiation, and PI3K-AKT signaling pathway. The gene discussed is PIK3CA; the disease is atherosclerosis.