The level of EGF inversely correlates with the chronic pathological index of the kidney, suggesting its role in renal tissue remodeling (Segarra et al., 2019; Mejia‐Vilet et al., 2021). TGF-β1 is related to proliferative LN, highlighting its influence on disease severity (Susianti et al., 2015). Activin A relates to vasculitis cell infiltration, the number of crescentic glomeruli, and fibrosis (Kadiombo et al., 2017). The gene discussed is TGFB1; the disease is vasculitis.