In a study examining the correlation of urinary VCAM-1 with nine renal histopathological manifestations, such as glomerular leukocyte infiltration, intracapillary proliferation, cellular crescents, fibrin-like necrosis, glomerulosclerosis, interstitial inflammation, fibro crescents, interstitial fibrosis, and tubular atrophy, urinary VCAM-1 was closely linked to fibro crescents. The gene discussed is VCAM1; the disease is glomerulosclerosis.