IFNG and systemic lupus erythematosus: The expression levels of biomarkers, including serum and urinary IFN-γ, CXCL16, and soluble urokinase plasminogen activator receptor (uPAR), were found to be notably greater in LN patients than in normal control subjects.These levels associated with the activity of pathological lesions in renal tissues, effectively reflecting disease activity, renal injury, and pathological lesions in SLE patients (Wen et al., 2018).