IL6 and rheumatoid arthritis: Correspondingly, the metabolite, 1-oleoyl-sn-glycero-3-phosphocholine (OPGC), in the inhibited choline phospholipid metabolism pathway is downregulated in the plasma of RA patients and participates in the pathogenesis of RA by modulating the IL-6/JAK signaling pathway (Figure 2) (Su et al., 2022).