While recurrent TP53 mutations and LOH on chromosome 17 (chr17) are known genomic aberrations in HGSC and contribute to tumor evolution [22, 37, 38], the concurrent display of both copy number values and LOH revealed a striking pattern in the bird’s-eye view: regardless of copy number gains and losses in chr17, all but 5 patients presented a complete LOH in the whole chromosome (Fig.   4). The gene discussed is TP53; the disease is neoplasm.