METTL16 and liver cancer: To evaluate the effects of METTL16 on liver cancer cells (ie, Huh7, Hep3B, HepG2, PLC/PRF/5, and SNU182), we performed small-interfering RNA–mediated knockdown and overexpression experiments for METTL16 using liver cancer cell lines (Supplemental Figure S4A, http://links.lww.com/HC9/B10).