Furthermore, we compared the gene-level (not the IR) expression of Notch receptors (ie, NOTCH1, NOTCH2, NOTCH3, and NOTCH4) and ligands (ie, JAG1 [jagged canonical notch ligand 1], JAG2 [jagged canonical notch ligand 2], DLL1 [delta like canonical notch ligand 1], and DLL4 [delta like canonical notch ligand 4]) using the pooled data of liver cancer, demonstrating that int-CA prominently expressed Notch ligands and receptors compared to the other tumor types (Figure 3E). This evidence concerns the gene JAG1 and liver cancer.