We performed proteomic sequencing of tumor tissues from each group, and the results of differential gene‐based gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses showed that USP22 was closely associated with biological functions, such as cell communication, cell motility, EV secretion, ECM‐receptor interaction, and focal adhesion (Figure 1G–I). This evidence concerns the gene USP22 and neoplasm.