RAB42 and cancer: ROC curves for pan-cancer were subsequently plotted, and the plots showed that RAB42 overexpression exerts diagnostic potential (AUC > 0.8) for 16 malignancies: CHOL (AUC = 0.90), ESCA (AUC = 0.84), GBM (AUC = 0.98), LGG (AUC = 0.84), OV (AUC = 0.98), PAAD (AUC = 0.95), KIPAN (AUC = 0.91), KIRC (AUC = 0.96), KIRP (AUC = 0.91), LAML (AUC = 0.96), SKCM (AUC = 0.90), STAD (AUC = 0.90), STES (AUC = 0.89), TGCT (AUC = 0.94), UCS (AUC = 0.88), and GMBLGG (AUC = 0.88) (Figures 2E–X).