PCSK1 and familial pancreatic carcinoma: Employing inhibitors including Nec-1 (necroptosis inhibitor), Fer-1 (ferroptosis inhibitor), Z-Vad-FMK (apoptosis inhibitor), 3-MA (autophagy inhibitor), DFO (iron ions chelator), tetrathiomolybdate (TTM) (copper ions chelator), and NAC (antioxidant), and monitoring cell viability with the CCK-8 assay, we found that TTM and NAC could significantly reverse the cell death in pancreatic cancer cells caused by EB (Figure 3A).