As for DNMT3AMu-AML patients, they displayed similar Teff and memory T cell proportions to HDs (all P ≥ 0.35), but a significantly decreased CD8 Tn than HDs (P = 0.037); within memory T cells, DNMT3AMu-AML patients displayed a tendency of increased Tcm and decreased Tem in CD4 cells compared with HDs (both P = 0.053), respectively. This evidence concerns the gene CD4 and acute myeloid leukemia.