Its use inhibits α-glycosidase activity and reducespostprandial blood glucose levels.24 Instreptozotocin (STZ)-induced diabetic rats, vitexin exhibits protectiveeffects via alleviating GPX4-mediated ferroptosis and improved spatiallearning and memory retention via increases in superoxide dismutase(SOD) and glutathione peroxidase (GPx).25 Studies of the vascular protection effect and underlying mechanismof vitexin in diabetes remain limited. The gene discussed is GPX4; the disease is diabetes mellitus.