VMP1 and neoplasm: In pancreatic cancer, VMP1 is upregulated under stress conditions and is associated with Kirsten rat sarcoma viral (KRAS) oncogene activation, contributing to tumor initiation and chemoresistance (Lo Ré et al., 2012; Gilabert et al., 2013; Loncle et al., 2016; Ropolo et al., 2020; Bai et al., 2021).