Investigations: Other than a borderline high CBC and erythrocyte sedimentation rate (ESR) (CBC-11,000, ESR-25, CRP-6) and positivity of antinuclear antibody (ANA), the other investigations were negative (Mantoux -Negative; Chest X-ray PA view- within normal limits (WNL); Serum calcium and angiotensin-converting enzyme (ACE) levels- WNL; Venereal Disease Research Laboratory Test for syphilis (VDRL)- Non-reactive; Urine routine microscopy- WNL; Rheumatoid (Arthritis) Factor (RA Factor) <10, C3 and C4 levels: normal). This evidence concerns the gene ACE and arthritic joint disease.