Consistent with our analyses based on genes in the top decile of expression specificity for each defined cell population, cells with high cell-trait (schizophrenia) association scores were concentrated among those annotated as L4-RORB-LRRK1 neurons (Figure 2C), with increasing scores across the developmental trajectory (standardized beta = 0.41; p < 2.2 × 10−16) (Figure 2D). This evidence concerns the gene RORB and schizophrenia.