In AngII-induced AAA mice, the diameter of AAAs showed a significant increase in the group of mice treated with exosomes and clodronate liposomes compared to the group treated with exosomes alone(2.41verus 1.44 ± 0.4009 cm,95%CI: 0.04558 to 1.894).(Fig. 4A) .Similar results were observed in the CaCl2-induced AAA model(2.16verus 1.22 ± 0.3421 cm,95%CI: 0.1512 to 1.729) (Fig. 4B). This evidence concerns the gene AGT and triple-A syndrome.