In addition, elevated IgA 1/2 bisecting glycoforms, declined IgA diantennary glycoforms, and increased IgA 1/2 asialylation levels were observed in PBC patients.314 The presence of IgG2 agalactosylation showed a positive correlation with various stages of PBC,314 indicating the potential significance of Ig glycoforms as biomarkers and for monitoring disease progression in autoimmune cholestatic liver diseases. Here, CD79A is linked to primary biliary cholangitis.