To assess the temporal dynamics of NfL accumulation in the plasma after stroke, blood sample collections were performed at 24 h, 1 week, 2 weeks, 3 weeks, 4 weeks, 5 weeks, 6 weeks, and 7 weeks after induction of DH stroke in aged (20- to 23-month-old) male mice. The gene discussed is NEFL; the disease is Stroke.