CD4 and tuberculosis: WHO recommends the use of Lateral Flow LAM Assay (LF-LAM) for the diagnosis of active TB in people living with HIV in those with signs and symptoms of TB (or) with advanced HIV diseases (or) seriously ill (or) CD4 count < 200 cells/mm3 (IP settings) or < 100 cells/mm3 (OP settings) irrespective of signs and symptoms of TB [34].