After silencing KLF7 expression, the viability of HCT116 and SW480 cells was dramatically diminished (p < .01, Figure 2(c)), and the invasion and migration abilities of cells were also reduced (p < .01, Figure 2(d)), indicating that KLF7 silencing curbed CRC cell invasion and migration. This evidence concerns the gene KLF7 and colorectal carcinoma.