In addition to the TCGA database showing a significant positive correlation between the AR or KLK3 expression with PEX10 expression (Figs. 4K and S4F, G), we also found a considerable positive correlation between AR protein and PEX10 expression level by immunohistochemistry staining of tissue microarray from prostate cancer patients (n = 70, P < 0.0001) (Fig. 4L, M). Here, AR is linked to Familial prostate cancer.