LRRK2 and Parkinson disease: We therefore evaluated expression changes of the LRRK2int (cases vs controls) in whole blood mRNA and found that 28.9% (109/377) of the LRRK2 interactors presented significant changes, among which only 13 showed a similar trend of alteration (4 up-regulated and 9 down-regulated) in both the sPD and LRRK2-PD cases.