For example, PD-related inflammation both in the Central Nervous System (CNS) and at the periphery, was linked to an increased LRRK2 expression level and strengthened LRRK2 kinase activity in microglia and peripheral immune cells in sPD patients as compared to controls (Cook et al. 17; Di Maio et al. 18). Here, LRRK2 is linked to Platelet storage pool disease.