FGFR2 and Crouzon disease: The most common coding mutation responsible for Crouzon syndrome, one of the most common presentation of syndromic craniosynostosis, is a point mutation in exon 9 of the FGFR2 gene, in which a cysteine molecule is substituted by a tyrosine residue (p.C342Y) and the IIIC isoform of the receptor is affected (Peskett et al., 2017).