TTR and hydrops fetalis: The clinical manifestations of ATTR-CA are nonspecific HF symptoms such as dyspnea or edema, which can take years or longer from the first HF symptoms to diagnosis [3], and orthopedic symptoms such as carpal tunnel syndrome or neuropathy, which are caused by transthyretin amyloid deposition in soft tissue and can precede HF symptoms by up to 10 years [4, 5], contributing to the delay in diagnosis of ATTR-CA.