We painted the landscapes of monocyte-macrophages and identified 5 distinct subsets including monocytes, C1QB+ macrophages, HSPA1B+ macrophages, IL-1B+ macrophages, and TMSB4X + macrophages in the intestinal mucosa from Crohn’s disease patients (Fig. 2a). The gene discussed is C1QB; the disease is Crohn disease.