Furthermore, we observed copy number gains or amplifications of the TPST2 gene (Fig. 6a) and significantly increased TPST2 mRNA expression (Fig. 6b) in various cancers, with higher TPST2 expression correlating with poorer prognosis in several cancer types, including BRCA, HNSC, OV, SARC, STAD, and UCEC (Fig. 6c). The gene discussed is TPST2; the disease is cancer.