According to this hypothesis, an earlier or stronger recognition (a stronger expression of R or Avr proteins and/or a stronger affinity between the R and Avr haplotypes) would lead to an earlier and/or stronger activation of downstream resistance responses, and consequently to an early inhibition of fungal infection (i.e. at the stomata), and hence to a stronger resistance. This evidence concerns the gene NLRP6 and fungal infectious disease.