In the GSE98895 data set, APOBEC3G, CD27, CX3CR1, GZMA, IL32, IRF1 and TLR5 were up-regulated in MS patients, while JAK2 and PTPN11 were down-regulated in MS patients, which were consistent with the results of AS (Fig. 6B). Here, TLR5 is linked to myeloid sarcoma.