As illustrated in Fig. 1C, SEH1L can serve as a potential diagnostic biomarker in COAD, esophageal carcinoma (ESCA), KICH, LIHC, lung squamous cell carcinoma (LUSC) and stomach adenocarcinoma (STAD) (AUC: 0.861, 0.803, 0.839, 0.753, 0.826 and 0.932 respectively). The gene discussed is SEH1L; the disease is colon adenocarcinoma.