AS is caused by iron deposition and lipid peroxidation in vascular endothelial cells.[62,63] Studies on ferroptosis in cardiovascular diseases have shown that multiple signaling factors are either directly or indirectly involved in iron ptosis, thus affecting iron metabolism and lipid peroxidation.[64] Iron ptosis has recently emerged as a therapeutic target in cardiovascular diseases.[65] Results of the present study showed that genes associated with iron ptosis (ACSL4, CBS, FTH1, and TFRC) were differentially expressed between the diseased and control groups. Here, CBS is linked to cardiovascular disorder.