Further correlation analysis supported the induction of immune cell infiltration and CXCL9, CXCL11, CXCL14, CXCL17, CXCR3, CXCR4, CXCR6, and GPR35 predicted better survival of HNSCC patients. The gene discussed is CXCL11; the disease is head and neck squamous cell carcinoma.