CTNNB1 and sarcoma: However, the final recognition of this rare novel entity was by a combination of observations by surgeons, radiologists, and pathologists to recognize this rare entity and obtain the final positive nuclear beta-catenin and distinctive CTNNB1 point mutation. Important are the unique features of the current case and the radiologic vascularity that corresponds to microscopic pathologic (Zellballen) vascular features, which resulted in proper diagnosis and management of this potentially metastasizing intermediate grade sarcoma.